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EPFL  >  SB  >  ISIC > Institute of Chem... > Biological Chemistry
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BIOLOGICAL CHEMISTRY

 

Laboratory of Biomolecular Magnetic Resonance (LRMB)

 

Prof. Geoffrey BODENHAUSEN

 

Structure and dynamics of biomolecules studied by nuclear magnetic resonance. Methodology. Intermolecular affinity.

Laboratory of Lanthanides Supramolecular Chemistry (LCSL)

 

Prof. Jean-Claude G. BÜNZLI

 

Coordination and supramolecular chemistry of 4f-elements. Design of lanthanide-containing luminescent probes based on: functionalized podand & macrocyclic receptors. Sensitization of NIR luminescence for imaging purposes. Recognition of heteropairs of metal ions by self-assembly processes. Development of luminescent liquid crystals. Luminescence spectroscopy in ionic liquids.

Laboratory of Ultrafast Spectroscopy (LSU)

 

Prof. Majed CHERGUI

 

Dynamics of Biosystems. Nanosystems. Many-body dynamics in non-polar media.Ultrafast X-ray science. Polar Solvation Dynamics at Interfaces

Laboratory of Organometallic and Medicinal Chemistry (LCOM)

 

Prof. Paul J. DYSON

 

Biphasic catalysis in water and ionic liquids. Design of ruthenium anticancer compounds. Transition metal clusters in novel synthesis and catalysis.
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Dr MER Gabor LAURENCZY

 

Hydrogen storage, "green" energy. High pressure chemistry - up to 2000 bar (pressure effect on kinetics and equilibria). Homogeneous catalysis, hydrogenation.

Chemical Synthesis Laboratory (LSYNC)

 

Prof. Karl GADEMANN

 

Isolation of natural products (bioprospecting). Synthesis of biologically active, stereochemically complex, natural products. Natural product hybrids and applications in chemical biology.

Laboratory of Therapeutic Proteins and Peptides (LPPT)

 

Prof. Christain HEINIS

 

Generation of new molecule designs for the use in therapy. Testing the therapeutic potential of the newly developed chemical structures

Laboratory of Regenerative Medicine and Pharmacobiology (LMRP)

 

Prof. Jeffrey HUBBELL

 

Fibrin Matrices. Targeted Drug Delivery. Synthetic ECM Analogs.
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Dr MER Christine WANDREY

 

Polyelectrolytes, charged macromolecules, and their organized structures

Laboratory of Protein Engineering (LIP)

 

Prof. Kai JOHNSSON

 

Chemical Biology. Protein Engineering. Directed Evolution of Protein Function.

Biomolecular Mass Spectrometry Laboratory (LSMB)

 

Prof. Yury TSYBIN

 

Method and technique development in biological mass spectrometry: Fourier Transform. Ion Cyclotron Resonance Mass Spectrometry. Time-of-Flight Mass Spectrometry. Ion-Electron and Ion-Photon Interactions.

Air and Soil Pollution Laboratory (LPAS)

 

Prof. Hubert van den BERGH

 

The main objective of the LPAS is to develop realistic models capable to simulate our atmosphere in the Planetary Boundary Layer.
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Dr Georges WAGNIÈRES

 

Tissue characterization and detection of malignancies by fluorescence spectroscopy and imaging. Photodynamic therapy for the treatment of cancers and other conditions associated with vascular or immune disorders. Biomedical optical spectroscopy and imaging. Preclinical and clinical development of photosensitizers, fluorescing markers and photodiagnostic instruments.

Laboratory of Physical Chemistry of Polymers and Membranes (LCPPM)

 

Prof. Horst VOGEL

 

Fundamental studies on the structure and dynamics of membrane proteins -Membrane-insertion and folding of proteins- Structure and function of ligand-gated ion channels and G protein-coupled receptors.Biophysical chemistry on surfaces.Development of new assays to study interaction between biomolecules.
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Dr MER Rudolf HOVIUS

 

Ligand-gated ion channels (structure, channel gating, cellular trafficking). GPCR signaling. Nanoparticles as bio-probes.
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Dr MER Gabrielle TUCHSCHERER

 

Switch-peptides

Laboratory of Glycochemistry and Asymmetric Synthesis (LGSA)

 

Prof. Pierre VOGEL

 

Asymmetric Synthesis of Natural Products and Analogs of Biological Interest (anti-cancer, antiviral agents, antibiotics).Glycomimetics as New Tools for Biology and Medicine. New Scaffolds for Biomolecules, for New Materials.New Organic Chemistry of Sulfur Dioxide.
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Dr MER Sandrine GERBER

 

Asymmetric synthesis of complex bioactive natural products and analogues.

Laboratory of Cellular Biotechnology (LBTC)

 

Prof. Florian WURM

 

Research at the LBTC is focused on the expression of recombinant proteins from suspension cultures of mammalian cells, the major approach to therapeutic protein production in the biotechnology industry. We are investigating three major thematic areas: Transient gene expression. Gene transfer for the generation of high-producing cell lines. Orbital shaking technology for the cultivation of animal cells in suspension.